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picture1_Heterocyclic Compounds Slideshare 82193 | Heterocyclic Compound  Ppt 3


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File: Heterocyclic Compounds Slideshare 82193 | Heterocyclic Compound Ppt 3
dr lamture s v head asso prof department of chemistry heterocycles ring compounds with elements other than carbon in the ring the most common elements to appear in heterocyclic compounds ...

icon picture PPTX Filetype Power Point PPTX | Posted on 09 Sep 2022 | 3 years ago
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       Dr. Lamture S.V.
       Head & Asso.Prof.
     Department of Chemistry 
          .
       Heterocycles
       Ring compounds with elements other than carbon in the ring.  The 
       most common elements to appear in heterocyclic compounds are 
       oxygen, nitrogen and sulfur.
       The aliphatic heterocycles are similar to the open chain analogues, 
       ethers, amines and sulfides.
       The aromatic heterocycles are similar to other aromatic compounds.
        Heterocyclic Nomenclature
        Replacement nomenclature (IUPAC recommended 1957)
             Oxygen oxa
             Sulfur         thia
             Nitrogen aza
        Lowest number assigned to the hetero atom with the highest precedence:  O > S > 
        N
                          S                                       NH
                                                           O
              thiacyclobutane                  1-oxa-3-azacyclopentane
         Hantzsch-Widman (1888)
         Suffixes
                          ring with nitrogen       ring without nitrogen
         Ring members   unsat’d         sat’d          unsat’d       sat’d
                3         -irine                -iridine            irene            irine
                4          ete                   etidine          ete               etane
                5              ole               olidine          ole               olane
                6              ine       perhydro__ine      in                ane
                7          epine   perhydro__epine  epin             epane
      You must know the * names
          O                        S                       N
                                                           H
      * oxirane             * thiirane                * aziridine
      ethylene oxide        ethylene sulfide          ethylene imine
      oxacyclopropane       thiacyclopropane          azacyclopropane
            N                                                   H
                                                             N
          N                        N                       O
       diazirane              1-azirine                 oxaziridine
                                                        oxazacyclopropane
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...Dr lamture s v head asso prof department of chemistry heterocycles ring compounds with elements other than carbon in the most common to appear heterocyclic are oxygen nitrogen and sulfur aliphatic similar open chain analogues ethers amines sulfides aromatic nomenclature replacement iupac recommended oxa thia aza lowest number assigned hetero atom highest precedence o n nh thiacyclobutane azacyclopentane hantzsch widman suffixes without members unsat d sat irine iridine irene ete etidine etane ole olidine olane ine perhydro ane epine epin epane you must know names h oxirane thiirane aziridine ethylene oxide sulfide imine oxacyclopropane thiacyclopropane azacyclopropane diazirane azirine oxaziridine oxazacyclopropane...

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