290x Filetype PPTX File size 0.91 MB Source: uoqasim.edu.iq
DNA biosensors
DNA biosensors
Principles of DNA biosensors
Principles of DNA biosensors
Nucleic acid hybridization
Perfect match
stable dsDNA, strong hybridization
One or more base mismatches
weak hybridization
Forms of DNA Biosensors
• Electrodes
• Chips
• Crystals
Types of DNA Based Biosensors
• Optical
• Electrochemical
• Piezoelectric
Immobilization of DNA Probe
Immobilization of DNA Probe
onto Transducer Surface
onto Transducer Surface
simple adsorption
onto carbon surfaces
Immobilization of DNA Probe
Immobilization of DNA Probe
onto Transducer Surface
onto Transducer Surface
Thiolated DNA for self assembly onto gold (or platinum) transducers
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