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Wet Granulation
Wet Granulation
The wet granulation technique uses the same
preparatory and finishing steps of direct
compression and dry granulation (dry
screening and mixing); it also involve
additional steps of wet massing, wet
screening and drying.
Steps of Wet Granulation
1.Mixing (blending)
of the drug, diluent
and disintegrant.
6.Mixing 2.Wet massing by
(blending) by addition of binder
addition of glidant or adhesive or
and lubricant. called granulation
agent.
5.Homogenizing 3.Granulation by
by second sieving sieving (wet
(dry screening). screening).
4.Drying.
Wet
Mixing Massing
Drying Wet
Screening
Dry Mixing
Screening
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