Overview
       Overview
        Motivation
        AIM
         ◦What is AIM?
         ◦Goals of AIM
         ◦Applications of AIM
        Clinical expert system : MYCIN
         ◦Introduction
         ◦How it works
         ◦Specification of the therapy selection 
          problem
         ◦Representation of Goals
         ◦Certainty factor
         ◦Partial derivation of the algorithm
      Motivation
      Motivation
      
       ‘Doctors in a box’ to diagnose 
       diseases.
      
       Community of computer 
       scientists and healthcare 
       professionals set a research 
       program - Artificial Intelligence in 
       Medicine (AIM) with the aim of 
       revolutionize medicine. 
      What is AIM?
      What is AIM?
      
       Clancey and Shortliffe :’Medical 
       artificial intelligence is primarily 
       concerned with the construction of AI 
       programs that perform diagnosis and 
       make therapy recommendations. 
       Medical AI programs are based on 
       symbolic models of disease entities 
       and their relationship to patient 
       factors and clinical manifestations’
      
       AI specialized to medical applications
      
       Employ human- like reasoning 
       methods in the programs
      
       AIM use ‘machine learning’ to use 
       and create knowledge.
      
       Machine learning - computers that 
       can learn from experience 
      
       Use – stored data used in diagnosis
      
       Creation - analyse the relationship 
       within the data to come up with 
       new results
      
       Used in Drug discovery 
      Goals of AIM?
      Goals of AIM?
      
       Expert computer programs for clinical 
       use
      
       Dissemination of the best medical 
       expertise to geographical regions 
       where that expertise is lacking
      
       Making consultation help available to 
       non-specialists not within easy reach 
       of expert human consultants. 
      
       To formalize medical expertise