276x Filetype XLSX File size 0.02 MB Source: ncats.nih.gov
Column1 Column2 Column3 Column4
PI Organ System Cell Source EC Matrix
Christiano Skin iPSC, some primary Collagen, fibrin, laminin
Donowitz GI primary collagen IV
S. George microvascular-endothelial OK Stromal cells; collagen or
fibrinogen matrix
S. George tumor cell line and some primary Stromal cells; collagen or
fibrinogen matrix
S. George heart-cardiomyocytes iPSC and some primary Stromal cells; collagen or
fibrinogen matrix
liver-hepatocytes plus
nonparenchymal cells Hydrogel with stromal
Griffith (endothelial cells, Kupffer cells, primary and iPSC cells; matrix self-organized
stellate cells, fibroblasts and
immune cells)
tumor-breast cancer
Griffith metastasis in liver (can be any primary and cell lines Hydrogel with stromal
tumor type - have used breast, cells; matrix self-organized
prostate, and melanoma)
Healy microvascular-endothelial cells iPSC GFR-Matrigel; 0.2% Gelatin
Healy liver-hepatocytes iPSC GFR-Matrigel
Healy heart-cardiomyocytes iPSC small precent stromal cells
Healy fat-white, adipocytes cell line Hyaluronic acid hydrogel
healthy iPSCs fibrin
Vunjak-Nova heart-cardiomyocytes patients' iPSCs native tissue ECM
supporting non-myocytes
Vunjak-Nova liver-hepatocytes iPSC; cell lines; reporters stromal-fibroblasts
Vunjak-Nova bone - tumor iPSCs hydrogels
cancer cells native tissue ECM
Vunjak-Nova microvascular-endothelial iPSC stromal cells, collagen,
fibrin, or matrigel
Himmelfarb kidney-proximal tubule, Mostly primary, some iPSC
Himmelfarb kidney-derived microvascular Mostly primary, some iPSC pericytes
(i) Fibronectin
(ii) Gelatin
Parker cardiomyocytes, HUVEC iPSC, cell lines (iii) Laminin
(iv) Collagen
(v) Combinations
thereof
Taylor liver-hepatocytes, endothelial, primary, iPSC Collagen type 1
Kupfer, Stellate
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