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Les GCO à l’ESMO 2017 Les Groupes Coopérateurs en Oncologie (GCO) seront présents au congrès de l’ESMO (European Society for Medical Oncology), qui se tiendra du 8 au 12 septembre à Madrid. L’ESMO est le principal rendez-vous de la cancérologie au niveau européen au cours duquel sont partagés les résultats d’études cliniques sur le traitement des cancers. Les GCO présenteront leurs dernières études menées dans les cancers gynécologiques, digestifs, bronchiques ainsi que les cancers de la tête et du cou. 5 communications orales, 7 posters discussion et 8 posters portant sur des essais promus ou réalisés en collaboration avec l’un des membres des GCO. CANCERS DE LA TETE ET DU COU ......................................................................................................... p.2 CANCERS DIGESTIFS (COLORECTAUX ET NON COLORECTAUX) ........................................................... p.2 CANCERS GYNECOLOGIQUES ............................................................................................................... p.3 CANCERS DU POUMON ........................................................................................................................ p.4 1 Lettre d’information des GCO – 7 septembre 2017 GCO/IFCT 10 rue de la Grange-Batelière - 75009 Paris Tel: +33 1.80.96.08.03 http://www.gco-cancer.org/ CANCERS DE LA TETE ET DU COU GORTEC : Groupe Oncologie Radiothérapie Tête et Cou Poster display session Chemoradiotherapy versus radiotherapy in the treatment of salivary glands and nasal tumors: the GORTEC 2016-02 study Abstract CANCERS DIGESTIFS (COLORECTAUX ET NON COLORECTAUX) FFCD : Fédération Francophone de Cancérologie Digestive GERCOR : Groupe Coopérateur Multidisciplinaire en Oncologie Poster display session Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD Groups (Epitopes-HPV02 study) Abstract FFCD : Fédération Francophone de Cancérologie Digestive Proffered paper (oral) session Neoadjuvant FOLFOX 4 versus FOLFOX 4 plus cetuximab versus immediate surgery for high- risk stage II and III colon cancers: A phase II multicentre randomised controlled trial (PRODIGE 22) Abstract Prognostic value of methylator phenotype in stage III colon cancer treated with oxaliplatin- based adjuvant chemotherapy Abstract Poster display session FOLFIRINOX as induction treatment in rectal cancer patients with synchronous metastases (RCSM): final results of the FFCD 1102 phase II trial. Abstract Predictive factors for early progression during induction chemotherapy (IC) and chemotherapy-free interval (CFI). Analysis from PRODIGE 9 trial Abstract 2 Lettre d’information des GCO – 7 septembre 2017 GCO/IFCT 10 rue de la Grange-Batelière - 75009 Paris Tel: +33 1.80.96.08.03 http://www.gco-cancer.org/ PRODIGE 50 - ASPIK French: French double blind randomised study of aspirin versus placebo in resected stage III or high risk stage II colon cancer with PIK3CA mutation Abstract PRODIGE 51 - GASTFOX: Phase III randomised trial evaluating FOLFOX with or without DOCETAXEL (TFOX) as 1st line chemotherapy for locally advanced or metastatic oesophago- gastric adenocarcinoma Abstract CANCERS GYNECOLOGIQUES ARCAGY - Association de Recherche sur les CAncers dont GYnécologiques GINECO - Groupe d’Investigateurs Nationaux pour l’Étude des Cancers Ovariens et du sein Proffered paper (oral) session Quality of Life in Patients with Recurrent Ovarian Cancer (OC) Treated with Niraparib: Results from the ENGOT-OV16/NOVA Trial Abstract Poster discussion session : Efficacy of olaparib maintenance therapy in patients (pts) with platinum-sensitive relapsed ovarian cancer (PSROC) by lines of prior chemotherapy: Phase III SOLO2 trial (ENGOT Ov-21) Abstract The Exposure-Response Relationship of Niraparib in Patients with gBRCAmut and Non- gBRCAmut: Results from the ENGOT-OV16/NOVA Trial Abstract Safety and Efficacy of Niraparib in Elderly Patients (Pts) with Recurrent Ovarian Cancer (OC) Abstract BRCA1&2 tumoral and germline status for ovarian cancer patients in first line setting within the PAOLA-01 trial Abstract Long term quality of life among epithelial ovarian cancer patients: The GINECO case/control VIVROVAIRE Study Abstract 3 Lettre d’information des GCO – 7 septembre 2017 GCO/IFCT 10 rue de la Grange-Batelière - 75009 Paris Tel: +33 1.80.96.08.03 http://www.gco-cancer.org/ Poster display session Outcomes of the combination trabectedin and pegylated liposomal doxorubicin (T-PLD) in recurrent platinum-sensitive ovarian cancer (OC): a GINECO cohort study Abstract A GINECO phase II study of Navitoclax (ABT 263) in women with platinum resistant/refractory recurrent ovarian cancer (ROC) Abstract CANCERS DU POUMON IFCT : Intergroupe Francophone en Cancérologie Thoracique Presidential symposium Results of the phase III IFCT-0302 trial assessing minimal versus CT-scan based follow-up for completely resected non-small cell lung cancer (NSCLC). Abstract Proffered paper (oral) session Second or 3rd line Nivolumab (Nivo) versus Nivo plus Ipilimumab (Ipi) in Malignant Pleural Mesothelioma (MPM) patients: results of the IFCT-1501 MAPS2 randomized phase 2 trial. Abstract (under embargo until 10.09.17) Poster discussion session IFCT‐1502 CLINIVO: Real‐life experience with nivolumab in 600 patients (pts) with advanced Non‐Small Cell Lung Cancer (NSCLC): efficacy and safety of nivolumab and post‐nivolumab treatment in the French Expanded Access Program (EAP) Abstract Ultrasensitive detection of EGFR T790M mutation by droplet digital PCR (ddPCR) in TKI naïve non-small cell lung cancer (NSCLC) harboring EGFR mutation: results of the nationwide program Biomarkers France of the French Cooperative Thoracic Intergroup (IFCT). Abstract Retrouvez tous les abstracts sur le site de l’ESMO : http://www.esmo.org/Conferences/ESMO-2017-Congress/Abstracts 4 Lettre d’information des GCO – 7 septembre 2017 GCO/IFCT 10 rue de la Grange-Batelière - 75009 Paris Tel: +33 1.80.96.08.03 http://www.gco-cancer.org/
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